Estimating disease prevalence in two-phase studies

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چکیده

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Estimating disease prevalence in two-phase studies.

Disease prevalence is ideally estimated using a 'gold standard' to ascertain true disease status on all subjects in a population of interest. In practice, however, the gold standard may be too costly or invasive to be applied to all subjects, in which case a two-phase design is often employed. Phase 1 data consisting of inexpensive and non-invasive screening tests on all study subjects are used...

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ژورنال

عنوان ژورنال: Biostatistics

سال: 2003

ISSN: 1465-4644,1468-4357

DOI: 10.1093/biostatistics/4.2.313